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The Semaine Journal

Semaine Journal

Brain & Longevity

Thoughtful explorations of cognition, healthy aging, and the emerging science that connects them.

Start with our essential guide
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Lithium in Drinking Water: Understanding Your R...

Find out why lithium varies in drinking water, what non-detect means, and how EPA reporting limits differ from health references and intake targets.

Lithium in Drinking Water: Understanding Your R...

Find out why lithium varies in drinking water, what non-detect means, and how EPA reporting limits differ from health references and intake targets.

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Lithium at Different Ages: Pregnancy Through Ol...

What does lithium research tell us about different ages? Understand the pregnancy study, evidence gaps, and why aging findings do not apply to everyone.

Lithium at Different Ages: Pregnancy Through Ol...

What does lithium research tell us about different ages? Understand the pregnancy study, evidence gaps, and why aging findings do not apply to everyone.

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Lithium, Mood, and Depression: Understanding th...

Learn how water-lithium studies differ from prescription lithium treatment, and why regional mood findings cannot establish a supplement benefit.

Lithium, Mood, and Depression: Understanding th...

Learn how water-lithium studies differ from prescription lithium treatment, and why regional mood findings cannot establish a supplement benefit.

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Lithium Orotate for Memory: What Do We Know?

Learn what lithium orotate research says about memory, how it differs from carbonate trials, and which questions still need answers in people.

Lithium Orotate for Memory: What Do We Know?

Learn what lithium orotate research says about memory, how it differs from carbonate trials, and which questions still need answers in people.

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Can Lithium Reverse Alzheimer's? Reading the He...

The lithium headlines came from research in mice and human brain tissue. See what the study found and why it is not an established Alzheimer's treatment.

Can Lithium Reverse Alzheimer's? Reading the He...

The lithium headlines came from research in mice and human brain tissue. See what the study found and why it is not an established Alzheimer's treatment.

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Lithium Orotate vs. Carbonate: Forms, Amounts, ...

Compare lithium orotate and carbonate, learn to read elemental-lithium amounts, and understand the evidence and safety questions for each form.

Lithium Orotate vs. Carbonate: Forms, Amounts, ...

Compare lithium orotate and carbonate, learn to read elemental-lithium amounts, and understand the evidence and safety questions for each form.

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How Lithium Works in the Brain: A Plain-Languag...

What do GSK-3, tau, and cell signaling have to do with lithium? Understand the proposed mechanisms and why laboratory findings need human testing.

How Lithium Works in the Brain: A Plain-Languag...

What do GSK-3, tau, and cell signaling have to do with lithium? Understand the proposed mechanisms and why laboratory findings need human testing.

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Lithium and Brain Health: Key Studies Explained

Compare key lithium studies by population, form, design, result, and limitation. See how human trials differ from water studies and mouse experiments.

Lithium and Brain Health: Key Studies Explained

Compare key lithium studies by population, form, design, result, and limitation. See how human trials differ from water studies and mouse experiments.

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Lithium and Dementia: What the Evidence Shows

Understand the research linking lithium and dementia, including water studies, small human trials, and what the findings mean for supplements.

Lithium and Dementia: What the Evidence Shows

Understand the research linking lithium and dementia, including water studies, small human trials, and what the findings mean for supplements.

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Lithium and the Brain: What the Research Shows

Explore lithium and brain health: the human trials, the 2025 mouse study, drinking-water data, and the questions researchers are still testing.

Lithium and the Brain: What the Research Shows

Explore lithium and brain health: the human trials, the 2025 mouse study, drinking-water data, and the questions researchers are still testing.

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