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The Semaine Journal

Semaine Journal

Brain & Longevity

Thoughtful explorations of cognition, healthy aging, and the emerging science that connects them.

Start with our essential guide
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Brain Fog and Fatigue: Could a Nutrient Deficie...

Iron, B12, and other nutrients can contribute to fatigue or brain fog. Learn what a symptom-led evaluation can clarify and where supplement support fits.

Brain Fog and Fatigue: Could a Nutrient Deficie...

Iron, B12, and other nutrients can contribute to fatigue or brain fog. Learn what a symptom-led evaluation can clarify and where supplement support fits.

Eggs, a salmon fillet and a glass of milk on cream linen, vitamin B12 food sources.

Methyl-B12 and B12 Deficiency: Forms and Symptoms

Compare B12 forms, recognize possible deficiency symptoms, and understand why the right amount and treatment approach matter more than an active-form label.

Methyl-B12 and B12 Deficiency: Forms and Symptoms

Compare B12 forms, recognize possible deficiency symptoms, and understand why the right amount and treatment approach matter more than an active-form label.

Fresh leafy greens, lentils and citrus on cream linen, a still-life of folate-rich foods.

Methylated Folate and MTHFR: Understanding the ...

Learn how 5-MTHF and folic acid differ, what common MTHFR variants mean, and why Semaine uses methylated folate in Hormone Balance.

Methylated Folate and MTHFR: Understanding the ...

Learn how 5-MTHF and folic acid differ, what common MTHFR variants mean, and why Semaine uses methylated folate in Hormone Balance.

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Lifestyle and the Menopausal Brain: Everyday Su...

Explore sleep, movement, cardiovascular health, and meaningful connection during menopause, with a realistic reading of dementia-prevention research.

Lifestyle and the Menopausal Brain: Everyday Su...

Explore sleep, movement, cardiovascular health, and meaningful connection during menopause, with a realistic reading of dementia-prevention research.

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What Is Mild Cognitive Impairment (MCI)?

Learn how MCI differs from normal aging and dementia, why it does not always progress, and how evaluation can identify care and treatment options.

What Is Mild Cognitive Impairment (MCI)?

Learn how MCI differs from normal aging and dementia, why it does not always progress, and how evaluation can identify care and treatment options.

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Parkinson's in Women: Symptoms, Research, and Care

Parkinson's can affect women differently. Explore symptom patterns, research on sex differences, and why access to individualized specialist care matters.

Parkinson's in Women: Symptoms, Research, and Care

Parkinson's can affect women differently. Explore symptom patterns, research on sex differences, and why access to individualized specialist care matters.

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Cognitive Reserve: How the Brain Adapts to Change

Understand cognitive reserve and the research on learning, meaningful activity, and brain resilience. Explore practical habits without a promise of prevention.

Cognitive Reserve: How the Brain Adapts to Change

Understand cognitive reserve and the research on learning, meaningful activity, and brain resilience. Explore practical habits without a promise of prevention.

Walnuts, flaxseeds, and a glass dish of golden omega-3 capsules on cream linen, warm light.

DHA and the Aging Brain: Food, Supplements, and...

DHA is part of brain-cell membranes. Learn what food, blood-level studies, and supplement trials tell us about omega-3s and cognitive aging.

DHA and the Aging Brain: Food, Supplements, and...

DHA is part of brain-cell membranes. Learn what food, blood-level studies, and supplement trials tell us about omega-3s and cognitive aging.

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Autoimmune Brain Fog: Understanding Possible Co...

Brain fog can accompany autoimmune illness. Learn how fatigue, sleep, pain, inflammation, and thyroid changes can affect concentration and care.

Autoimmune Brain Fog: Understanding Possible Co...

Brain fog can accompany autoimmune illness. Learn how fatigue, sleep, pain, inflammation, and thyroid changes can affect concentration and care.

Fresh turmeric and ginger root on cream linen in warm light, anti-inflammatory wellness mood.

Why Do More Women Have Autoimmune Diseases?

Explore how genes, hormones, and other factors may contribute to autoimmune disease patterns, and why the explanation differs between conditions.

Why Do More Women Have Autoimmune Diseases?

Explore how genes, hormones, and other factors may contribute to autoimmune disease patterns, and why the explanation differs between conditions.

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Surgical Menopause and Your Brain: What to Know

Removing both ovaries differs from hysterectomy alone. Learn about abrupt hormone changes, brain research, and questions for your care team.

Surgical Menopause and Your Brain: What to Know

Removing both ovaries differs from hysterectomy alone. Learn about abrupt hormone changes, brain research, and questions for your care team.

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Early Menopause and Dementia Risk: What Studies...

Understand the link between earlier menopause and later dementia diagnoses, how surgical menopause differs, and what to discuss with your clinician.

Early Menopause and Dementia Risk: What Studies...

Understand the link between earlier menopause and later dementia diagnoses, how surgical menopause differs, and what to discuss with your clinician.

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