PMS & Period Support

Rated 4.7 stars
243 Reviews

Get it between -


60 days to try it and love it - or send it back

“Semaine clearly fills a need in the wellness market.”

“Semaine is helping improve options for period pain.”

“Semaine is grounded

in evidence based research.”

The Only Clinically Tested PMS Supplement

Semaine is the natural solution for PMS and period relief.

As part of our cycle, inflammation increases when we are menstruating. This causes cramping, bloating and PMS.

Semaine was designed with 9 powerhouse plant extracts and minerals to help your body when you need it the most, and we've conducted a clinical trial to show this.

Vegan • Non-GMO • Gluten-free • Sugar-free • Plant-based • Hormone-free • Drug-free • Cruelty-free •
Allison | Florida

"There have been many days where I laid in bed and prayed to die so the pain would stop on my cycle. I tried these for the first time this month and I feel alive."

JoJo | North Carolina

"I’ve tried literally EVERYTHING when it comes to my period. I finally found these and they are a GAME CHANGER!"

Cindy | Nevada

"I can’t believe how much Semaine has helped me already!! Usually on my first day bleeding I can’t get out of bed and have to just lie on my heating pad, but today I’ve worked with no pain."

Relief When You Need It

Start taking PMS & Period Support 1-2 days before your period starts or when your PMS symptoms begin. Take 2 pills at a time up to 4 times daily.

That's it.

Powerful, hormone-free and drug-free relief when you need it.


  • Aswhwagandha: stress and fatigue reducer*
  • Boswellia: soothes intestines*
  • Curcumin: supports healthy inflammatory response*
  • Green Tea: caffeine-free energy booster*
  • Magnesium: muscle relaxer to reduce cramps*
  • Quercetin: lessens histamine response*
  • Resveratrol: antioxidant found in red wine and chocolate*
  • Silymarin: liver booster from milk thistle*
  • Vitamin D3: vegan sunshine supports immunity*

Dive Deeper

The Science Behind Our Supplements

Our unique (and patented) PMS & Period Support formulation has been clinically tested to determine how it works and its efficacy.

It is the only PMS supplement that has been clinically studied and shown to be effective when taken just around your period.

Clinically Tested


women participated in the trial


age bracket

An independent 3rd party conducted clinical-trial registered at

Study Name: An Exploratory Investigation of Dietary Supplementation and the Effect on Common PMS and Menstrual Symptoms

Study design: crossover assignment where all participants experience both baseline menstrual cycle and

Dosage: 2 pills, 3x per day for 6 days

Masking: None

Primary Outcomes: Change in perceived discomfort associated with menstruation. Specifically, several of the most common menstrual symptoms: cramping, bloating gastrointestinal issues, mood swings, breast tenderness, among others.

Each endpoint will be reported by participants on a scale of perceived discomfort at the end of each menstrual cycle.

of participants reported less overall discomfort

of participants reported fewer mood swings

of participants reported milder period poops

of participants reported less bloating and cramps

Reduction in Discomfort

The average reduction in discomfort for each common PMS symptom

hs-CRP levels

Measured blood CRP levels during period.


Orders are shipped within 1 business day, and shipped by USPS for the USA and FedEx for international orders.

Most customers feel a difference within an hour of starting PMS & Period Support, and 92% of users reported less bloating during their first cycle

PMS & Period Support helps your body mount a health response to the inflammation that increases during your period.

Yes you can! They help in different ways and are the perfect combination if you struggle with unbalanced hormones and period discomfort.

Rated 4.7 stars
Based on 243 reviews
243 reviews
  • AW
    Audrika W.
    Verified Buyer
    I recommend this product
    Age Range 45 - 54
    My health issues Adenomyosis, Mood, Acne, Nausea, Bloating
    Semaine helped with Mood, Cramps, Energy, Fatigue, Headaches
    Rated 5 stars

    This has been a great alternative to OTC meds. This coupled with the daily support supplement and diet adjustments has postponed and may prevented me from having surgery due to the great relief I have from my symptoms while dealing with adenomyosis. I highly recommend it!

    Was this helpful?
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    Semaine Health

    Thanks, Audrika! Making lifestyle changes like you have is so awe-inspiring and not easy. Go you!!

  • JW
    Jennifer W.
    Verified Buyer
    I recommend this product
    Age Range 35 - 44
    My health issues Fibroids, Heavy Flow, Bloating, Nausea
    Semaine helped with Bloating, Mood, Cramps
    Rated 3 stars
    I give 1 thumb up!

    It helped with cramps a bit, but it caused me to clot more, which caused pain. It did help with my nausea as well, but I still give it 4 out of 5 stars for the natural ingredients. I wish it helped me more with my pain and heavy flow.

    Was this helpful?
    SH Profile picture for Semaine Health
    Semaine Health

    Hi Jennifer, thank you for your review! We've not heard of increased clotting before, so we appreciate your feedback. On the days where you're really experiencing a lot of pain, you can take up to 2 pills, four times a day (instead of the typical 2 times a day). Hopefully that helps!

  • JW
    Jolene W.
    Verified Buyer
    I recommend this product
    Age Range 45 - 54
    My health issues Heavy Flow, Bloating, Migraines, Mood, PCOS
    Semaine helped with Mood, Stress
    Rated 5 stars
    Sample Pack from Thrive

    I trialed this product for 12 days from Thrive Market. I have tried several of the ingredients as well as other pms/pmd products. I have anxiety, anger, irritability, and severe mood swings for approximately 10-15 days pre cycle. This stuff…amazing. I feel able to manage better even if I am somewhat emotional, not nearly as bad. I take it every single day now.

    Was this helpful?
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    Semaine Health

    Jolene, we're so glad you found us at Thrive! Thank you for giving us a try.

  • AK
    Ashley K.
    Verified Buyer
    I recommend this product
    My health issues Heavy Flow, Mood, PCOS, PMDD, Migraines
    Semaine helped with Migraines, Digestive Issues, Stress, Headaches, Cramps
    Rated 5 stars
    Truly life changing

    I have PCOS, PMDD and IBS that gets agitated during my cycle. Semaine helps with all of this by lessening the amount of pain I have, lessened headaches and lower levels of acid reflux. Truly worth the price to not have such a horrible time 7-9 days a month.

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    SH Profile picture for Semaine Health
    Semaine Health

    Thank you Ashley! We're so happy that our PMS & Period Support alleviates so many of your symptoms!

  • U
    Verified Buyer
    I recommend this product
    My health issues
    Semaine helped with Bloating, Cramps, Muscles, Energy, Fatigue
    Rated 5 stars
    No more painkillers

    I am someone that has extreme period cramps to the point where I will start throwing up and getting light headed if I don’t take any painkillers. I have been looking to switch to other options for a while now and thought I’d give Semaine a shot. My life is changed! I do not have to take any more painkillers. I maximum i took were 2 capsules 4 times a day on my second day. I can tell a difference in just one cycle of use. Thank you for making me periods so tolerable!

    Was this helpful?
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    Semaine Health

    You are welcome and thank you for such a lovely review! We started this company to help people like you and hearing your success story means so much!

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