Using two powerful plant extracts clinically studied to promote urinary tract health, help stop microbial build-up and support immunity.*
• NO ARTIFICIAL DYES
• NO GMOS
• NO ADDED CAFFEINE
• NO ADDED MELATONIN
• NO GLUTEN
• NO CARRAGEENAN
• NO DAIRY
• NO ARTIFICIAL FLAVORS
• NO SOY
• NO ARTIFICIAL DYES
• NO GMOS
• NO ADDED CAFFEINE
• NO ADDED MELATONIN
• NO GLUTEN
• NO CARRAGEENAN
• NO DAIRY
• NO ARTIFICIAL FLAVORS
• NO SOY
Loved by the Semaine Community
Even with a perfect hygiene routine, UTI-causing bacteria can still win. Our formula includes targeted nutrients for optimal urinary wellness.*
UTI Protection
Promotes bladder health and protects against bacteria.*
Ingredients
Cranberry phytosome and hibiscus extract work together to protect against and flush harmful bacteria to promote a healthy urinary tract.*
Kidney Health
Supports healthy kidney function and overall wellness.*
Ingredients
Hibiscus extract may help improve calcium oxalate elimination in urine. Potentially contributing to kidney stone prevention.*
Vaginal Wellness
Helps maintain healthy pH levels and vaginal flora*
Ingredients
Cranberry phytosome and hibiscus extract are high in antioxidants, which protect from damage caused by free radicals. Additionally, they support a healthy vaginal flora and pH levels, which contribute to overall vaginal wellness.*
Feel the Benefits
The bladder lining acts like a protective barrier, keeping urine and irritants from damaging the bladder. When it’s weakened, it can lead to leaks, infections, or other issues. Everyday habits like staying in sweaty clothes, holding in pee too long, or having sex can increase your risk of infection, and up to 90% of E. coli strains that cause UTIs are resistant to antibiotics. Each time you get a UTI, part of the bladder lining sheds to flush out bacteria. Over time, that shedding can leave the bladder more sensitive, increase urgency, and make you more prone to future UTIs.
Source: World Health Organization
Cranberries have long been used to support urinary health, thanks to natural compounds called proanthocyanidins (PACs) that help prevent bacteria like E. coli from sticking to the bladder. Our science-backed research revealed that Anthocran Phytosome, a patented cranberry extract that enhances bladder absorption, disrupts biofilm growth. This special structure helps your body absorb them more effectively and efficiently, allowing them to reach your bladder and start working with fewer doses. In a three-month study, 100% of participants stayed UTI-free—thanks to a formula that works smarter, not harder.
Source: Clinical Trial Registered NCT04958087
The bladder lining acts like a protective barrier, keeping urine and irritants from damaging the bladder. When it’s weakened, it can lead to leaks, infections, or other issues. Everyday habits like staying in sweaty clothes, holding in pee too long, or having sex can increase your risk of infection, and up to 90% of E. coli strains that cause UTIs are resistant to antibiotics. Each time you get a UTI, part of the bladder lining sheds to flush out bacteria. Over time, that shedding can leave the bladder more sensitive, increase urgency, and make you more prone to future UTIs.
Source: World Health Organization
Cranberries have long been used to support urinary health, thanks to natural compounds called proanthocyanidins (PACs) that help prevent bacteria like E. coli from sticking to the bladder. Our science-backed research revealed that Anthocran Phytosome, a patented cranberry extract that enhances bladder absorption, disrupts biofilm growth. This special structure helps your body absorb them more effectively and efficiently, allowing them to reach your bladder and start working with fewer doses. In a three-month study, 100% of participants stayed UTI-free—thanks to a formula that works smarter, not harder.
Source: Clinical Trial Registered NCT04958087
Support My Best Self
Backed by Science, Proven by You.
Week 2
Less Pressure, More Comfort
Cloudy urine clearing up*
Peeing more comfortably*
Protection activated*
Week 6
Bladder Strong, Confidence High
Sleeping through the night*
Less leakage, drier underwear*
Fewer bathroom trips*
Week 10
Goodbye UTIs, Hello Balance
No-fear intimacy*
Enjoying long car rides*
Goodbye, chronic UTIs*
Learn More
Third-party trial conducted in 2022 by Indena and the University of Pavia (Clinical Trial Registered NCT04958087)
Our 'Never Ever' Ingredients
We're committed to providing clean, high-quality supplements, which is why we intentionally omit these.
Feel the Benefits
No GMOS
No Artificial Dyes
No Artificial Flavors
No Carrageenan
No Gluten
No Added Caffeine
No Added Melatonin
No Parabens
No Dairy
No Soy
We like to stay lean and clean so we leave out any unnecessary or harmful chemicals.
Our 'Never Ever' Ingredients
We like to stay lean and clean so we leave out any unnecessary or harmful chemicals.
We're committed to providing clean, high-quality supplements, which is why we intentionally omit these.
No GMOS
No Artificial Dyes
No Dairy
No Artificial Sweeteners
No Gluten
No Gelatin
No Added Melatonin
No Parabens
No Soy
No Artificial Flavors
Feel the Benefits
Our Philosophy
Semaine was born from love when Dr. Matt developed our very first product for his wife, Lar—now our CEO—after she finally found relief from debilitating pain she thought would never end. Ever since, we’ve built every solution on that same intentional, science-backed foundation, offering shame-free support for women’s health. Whether you’re managing stress, balancing hormones, or improving gut health, our research-driven formulas meet you where you are—helping you feel good today and even better over time.
Science-Backed
Research-Driven
Thoughtfully Made
Our story
Answers for Peace of Mind
What are the benefits of Urinary Tract Cleanse & Protect?
Urinary Tract Cleanse & Protect is a science-backed supplement that targets urinary health from multiple angles. Powered by clinically studied cranberry phytosome and kidney-supporting hibiscus extract, it helps flush harmful bacteria, reduce the risk of recurrent UTIs, and support long-term bladder resilience. Designed with bioavailability and safety in mind, it’s a proactive daily capsule that helps you feel protected and comfortable, every day.
How do I take Urinary Tract Cleanse & Protect?
Take 1 capsule daily. For extra protection, take 1 capsule every 12 hours.
Can I take more than one supplement?
We designed all of our supplements to work effectively together. We are complex humans, so we need different supplements at different stages of life. However, it's always a good idea to check with your doctor if you are starting any new supplement and taking one or more medications. We have a white paper that you can share with your doctor that explains the formulation, dosage, and clinical trial results so that they can help you make an informed decision: White Papers
Are your supplements FDA-regulated?
Semaine supplements are FDA-regulated, not approved, just like any supplement on the market. However, our supplements are made in an FDA facility and we third-party test all of our products.
What is your happiness policy?
If you are not completely satisfied with your first Semaine purchase, we’re happy to provide a full refund for up to two bottles within 60 days of the original shipping date of your first bottle. Shipping is not refundable. Our support team will be glad to help you with this process. For more information, please read our Customer Happiness Guarantee page in our Help Center.
How do I start a subscription?
Each product page has a subscription or one-time purchase option. To start a subscription, click the "Subscribe and save" option.
Chat with Cath,
Co-founder of Semaine!
Meet Cath, the driving force behind Semaine as our Head of Operations and the friendly face of our customer service team. She's here to personally address all of your questions.
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