Skip to content

Get $5 off $25+ with SAVE5

4.7 · 906 reviews
Recommended by 300+ clinicians
DAILY SUPPORT BETWEEN UTIs

The UTI is gone. The vulnerability may not be.

A UTI can leave your bladder’s protective lining worn down. Even after the pain is gone, the lining may still be recovering, and during that window your bladder can be more vulnerable to another infection. This formula is built for that time between UTIs.

  • Supports the bladder lining and urinary environment*
  • Patented cranberry phytosome, designed for 3× better absorption
  • One capsule daily for support between UTIs

Buy 2, Get 1 Free · $20.66/bottle

Buy 2, Get 1 Free. Exclusive to this page, while it lasts.

Semaine Urinary Tract Cleanse + Protect
As seen in
The overlooked window

Feeling better does not always mean your bladder is back to its usual state.

The inside of the bladder is lined with protective tissue called the urothelium. It helps form a barrier between the bladder wall, urine, and bacteria.

During a UTI, infection and inflammation can disturb this protective lining. A growing body of urology research points to weakened defenses in this lining as one reason UTIs return, though exactly how this happens is still being studied.

  1. The flare hits

    You feel it, see a clinician, and the active infection gets treated. The pain finally lets up.

  2. Symptoms fade

    You feel like yourself again. But underneath, your bladder’s lining and the conditions in your urinary tract may still be recovering.

  3. The window most people skip

    This is when daily support matters most: caring for your bladder between UTIs, not only when symptoms appear.

Recurrence isn’t proof you did something wrong.

Right after an infection, your bladder is most vulnerable while its lining is still recovering. Daily support during that window is one of the simplest ways to help reduce the odds that a UTI comes back.*

Why one UTI can sometimes be followed by another.

44%
of women have another UTI within 6 months of the first
Foxman B., Am J Med 2002
80%
of microbial infections in the body involve biofilms
National Institutes of Health

Recurrence does not have one universal cause. Researchers are studying how bacteria attach and remain, along with inflammation and changes in the bladder’s protective lining. The takeaway is simple: supporting your bladder between UTIs matters.

Cited research

Citations do not imply endorsement or affiliation.

Built for what comes next

Daily support, so your bladder is less vulnerable to the next UTI.

  • 120 mg cranberry phytosome
  • Standardized cranberry PAC-A
  • Standardized hibiscus extract
  • Third-party tested
  • One capsule daily

This is for you if…

Best match A great fit
Not the
right fit
Not the right fit
You’ve had recurring UTIs that keep coming backRecurring UTIs that keep coming back
You’ve tried cranberry pills before and nothing has changedYou’ve tried cranberry pills and nothing changed
You’re willing to take something dailyWilling to take something daily
You are looking for care for current urinary symptoms
×
Urinary Tract Cleanse + Protect bottle with capsule
Two parts of UTI recurrence

The bacteria matter. So does the barrier.

The bacteria: Bacteria can attach to the urinary tract and form protective communities called biofilms. Our cranberry targets biofilms, not just individual bacteria. Its studied anti-adhesion activity may make it harder for unwanted bacteria to hold on.

The barrier: The urothelium, your bladder’s protective lining, helps shape the conditions bacteria encounter in the urinary tract. Hibiscus supports that lining and urinary environment as part of a daily routine.*

When UTIs keep coming back, it’s usually about more than flushing bacteria out. Both how the bacteria behave and how well your bladder’s natural defenses hold up can play a role.

Without support: biofilm matrix on bladder wall
With daily Semaine use: PAC-A anti-adhesion layer on bladder wall
The Formulation

Two Ingredients. Complete Bladder Support.

Cranberry bioavailability varies wildly, and hibiscus is usually under-dosed. This formula uses the forms that actually work in the bladder.

Cranberry phytosome

Cranberry Phytosome

Anthocran® by Indena · Standardized PAC-A

Regular cranberry barely absorbs. The active compounds (PAC-A) pass through before they reach the bladder. Indena's phytosome form binds PAC-A to phospholipids, so enough actually gets there.

Hibiscus extract

Hibiscus Extract

Standardized anthocyanins

Hibiscus anthocyanins shift urinary pH and support the bladder's own lining, making the environment less welcoming to bacteria. The effect compounds with daily use.

Woman taking a capsule

Not all cranberry is the same.

Best choice Semaine
Cleanse + Protect
Semaine Urinary Tract
Cleanse + Protect
Standard
Cranberry
3x more bioavailable cranberry PACs
Targets biofilm, not just bacteria
Clinically dosed (120mg standardized)
Urinary environment support (hibiscus)
Daily bladder environment support
Microbiome safe

Independently studied. Third-Party Tested.

89%
of women reported less bladder irritation*
81%
of women reported fewer night-time bathroom trips*
55%
reduction in microbial growth after 12 hours vs. control

*Based on a third-party consumer perception study of 48 women age 40+ taking Urinary Tract Cleanse & Protect for 5 months

Tilted bottle with capsules

Advised by a Dedicated Medical Advisory Board

We partner with respected medical experts in gynecology, urology, and beyond who help shape our commitment to rigorous science and accessible, evidence-based education for women.

  • Dr. Michael Lewis
    OBGYN
  • Dr. Barbara Chubak
    Urologist
  • Dr. Jackie Crowell
    PT, DPT
120mg
Cranberry phytosome (clinically dosed)
90 Day
Happiness Guarantee
“Have not had a UTI since I started taking them.”
Carolyn N. · Verified Buyer · Age 65+
“I get frequent UTIs because of my endometriosis. I took 1 pill a day for 4 days and the symptoms went away.”
Lauren L. · Verified Buyer · Age 35–44
“I used to have UTIs almost every couple weeks. I haven't had one in almost 2 years.”
Janet M. · Verified Buyer · Age 55–64
Bottle held with leaves
Timeline

Build the between-episode habit.

  1. Day 1

    Start the routine.

    Take one capsule with water, at any time of day.

  2. Week 2

    Make it consistent.

    Daily use creates a simple between-episode habit.

  3. Month 1

    Keep supporting the urinary environment.

    Consistency matters more than reacting only when discomfort appears.

  4. Month 3

    Complete the recommended trial.

    Evaluate how you feel, backed by the 90-day money-back guarantee.

Real names. Real comments.

Their words. Not ours.

  • 5,000,000+ capsules sold
  • 3,200+ verified reviews

A few of the comments women leave us on Facebook. There are thousands more.

Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
Facebook comment from a Cleanse & Protect customer
100% MONEY-BACK GUARANTEE

Feel the shift in 90 days, or your money back.

Root-level change takes a season, not a weekend. Give it the full 90 days. If you don’t feel the shift, we’ll refund every cent. No fine print.

Choose Your Supply

Most urinary supplements address the bacteria. We address the biofilm.

One-time purchase, no subscription. Best for women who want daily urinary support and long-term bladder comfort.

Single Bottle

1 bottle

$30.99
+ $4.99 shipping

1 capsule. Every day. It's that simple.

1

1 capsule daily

With water. Any time of day.

2

Stay with it for 90 days

Most women feel the shift by month 3. It compounds.

Bottle with beaker and leaves
Common Questions

FAQs

How is this different from regular cranberry supplements?
Most cranberry supplements use standard extracts with poor bioavailability. The PAC-A compounds that do the work don’t reach bladder tissue in meaningful concentrations. The phytosome technology in our cranberry binds the active compounds to phospholipids, dramatically improving absorption by 3× the standard cranberry extract.
Do I only take it when I feel something coming on?
This is designed for daily, consistent use between episodes, not reactive single doses. If you have urinary symptoms now, contact a healthcare professional rather than waiting on a supplement.
How long until I notice a difference?
Experiences vary. We recommend a consistent 90-day routine, then evaluating how you feel. Your purchase is backed by the 90-day money-back guarantee.
Is this a replacement for antibiotics?
No. Urinary Tract Cleanse + Protect is a dietary supplement for daily urinary support, not care for an active UTI. If you have urinary symptoms, contact a healthcare professional promptly and follow your clinician’s advice, including prescribed antibiotics when appropriate. Seek urgent guidance for fever, back or flank pain, blood in the urine, worsening symptoms, or symptoms during pregnancy. This formula is positioned for a daily routine between episodes, not as a replacement for medical care.
Can I take it alongside other supplements?
Yes. The formula is clean and unfussy. If you’re taking prescription medications, check with your pharmacist. Hibiscus can interact with some drugs at high doses.
Cleanse and Protect with Pre+Probiotic
The Bladder Resilience Protocol

You’ve supported the bladder. Now support the source.

Most bacteria that cause recurring UTIs originate in the gut, then migrate.

  • Cleanse & Protect targets unwanted bacteria in the bladder
  • Pre+Probiotic supports the gut microbiome where they live
  • Together, daily protection at the root

View Supplement Facts:

Urinary Tract Cleanse & Protect

Supplement Facts

Urinary Tract Cleanse & Protect Supplement Facts panel

Pre+Probiotic For Women

Supplement Facts

Pre+Probiotic For Women Supplement Facts panel

Continue with Cleanse & Protect only

Why add Pre+Probiotic to your routine?

  • Supports the gut microbiome where unwanted bacteria can live

  • Complements Cleanse & Protect’s bladder-focused work

  • Daily, root-level support, inside out

  • Built for women navigating recurring patterns

Gluten free
Dairy free
Soy free
No artificial colours
Third-party tested
Non-GMO

Your bladder environment is the work.

1 capsule a day. The shift compounds over 90.

One-time purchase · Free shipping over $60 · 90-day money-back guarantee

Your Cart