No water after 6, and still up at 3?
See a difference in 90 days, or your money back.
A bladder can feel full before it is actually full. Tap each sign that sounds like you. Two or more? They share one cause, and one daily fix.
*Self-reported, consumer perception study of 48 women aged 45+.
What happens at night
Sign 1 of 6 · Still up at 3
First it was no water after dinner. Then nothing after 5. Now you go to bed thirsty, and the 3am trip happens anyway.
Why it happens: Your bladder isn’t a bucket that only signals when it’s full. When its environment is irritated, its nerves can send “full” early, however little you drank.
Sign 2 of 6 · Barely a trickle
You hurry down the hall like it can’t wait. Then a trickle, and you stand there wondering what that was about.
Why it happens: “Full” is a message, not a measurement, and an irritated bladder sends it at a smaller volume. The urge is real. The volume just isn’t there yet.
What it does to your sleep
Sign 3 of 6 · Awake at 3:15
The trip takes two minutes. Then you lie there doing the math: if I fall asleep right now, I still get three hours.
Why it happens: Your brain hears “full” and does what it always does with that news: it wakes you. Not halfway. Completely. So you get back into bed tired, but suddenly alert.
Sign 4 of 6 · Sleep aids fail
Melatonin, magnesium, a cooler room, no screens after 9. You’re out by 11. You’re still up at 3.
Why it happens: Falling asleep was never the problem. Being woken up was. A sleep aid works on the first. The early signal from your bladder causes the second.
How it follows you into the day
Sign 5 of 6 · Mapping bathrooms
The aisle seat. The table near the back. The drive home with the gas station on it. It’s a layer of planning you never used to need.
Why it happens: The same early “full” signal runs all day, not just at night. When it fires at a smaller volume, you learn to stay close to a bathroom, just in case.
Sign 6 of 6 · Started in my 40s
It isn’t just age, and it isn’t something you have to live with.
Why it happens: The timing isn’t a coincidence. As estrogen declines, bladder and urethral tissue thins and the urinary environment shifts. That’s a change you can support, every day.
If two or more sounded like you, you don’t have six problems. You have one.
Your bladder is sending “full” too early, and broken sleep makes every wake-up easier. One cause, one daily fix: one capsule of Urinary Tract Cleanse & Protect.
See the daily fix ↓Urinary Tract Cleanse & Protect. 78% of women in our study reported fewer nighttime bathroom trips by month 3.* 3 bottles, 1 capsule a day. $23.30 a bottle.
Subscription. Renews every 3 months at $69.91. Skip or cancel anytime.
See a difference in 90 days, or your money back.
*Self-reported, consumer perception study of 48 women aged 45+.
Think of a smoke alarm so touchy it trips on shower steam. Nothing is burning. A touchy bladder works the same way.
Where it says “full”Same amount inside
Your bladder wall is living tissue, full of nerve endings. They report two things to your brain: how stretched it is, and what the environment inside is like. So needing to go is a message, not a measurement. And an irritated bladder sends it early.
The threshold drops
An irritated urinary environment can make bladder nerves fire at a smaller volume, so “full” arrives early.
The night breaks
Your brain hears full and wakes you. You’re up at 3, doing math about how much sleep is left.
The cycle tightens
Broken sleep is lighter sleep, and lighter sleep wakes at signals you once slept through. Each interruption makes the next one easier.
Deep sleep: you sleep through
Lighter sleep: the same signal wakes you
Wake lineSignal from your bladder
You’re not bad at sleep. Showering less won’t calm a touchy alarm, and cutting water won’t calm a sensitive bladder. Neither will a sleep aid. The bladder sending the signal is what needs daily support.
Here’s what women reported when they supported it every day.
Our five-month study of Urinary Tract Cleanse & Protect
64% of women reported less bladder irritation in month 1, and 83% by month 2. Then the nights caught up.*
reported fewer nighttime bathroom trips by month 3*
By month 4, even more women reported improvement:*
81% reported fewer nighttime bathroom trips89% reported less bladder irritation
*Self-reported improvement, five-month consumer perception study of 48 women aged 45+.
Calmer inside, so the signal comes when it should. Bacteria that grab the bladder wall and stay there irritate it; cranberry makes grabbing on harder. Hibiscus supports the bladder’s own lining.
Cranberry phytosome120 mg Anthocran® by Indena, about 3x better absorbed than standard cranberry extract
Hibiscus240 mg flower extract, supports the bladder lining
1 capsule a day
30 capsules, 30 days. Nothing to time around bedtime.
In a clinical study of our cranberry, biofilm growth in urine was reduced by up to 55% after just 1 week.†
†Double-blind, cross-over study of the cranberry phytosome in this formula, in healthy volunteers. Separate from the consumer perception study.
Amazing product that does what it claims to do!
“…I’m perimenopausal and I was really starting to feel like I was imagining the symptoms but they are very hard to ignore. I started noticing I wasn’t feeling any urgency within a few days of starting it. …”
Urinary Tract Cleanse & Protect
The signal fires early. Support the bladder that sends it.
600+ clinicians recommend Semaine.
Wonderful Product
“It has been wonderful...only up once at night sleeping so much better...Also can go so much longer when I go out for shopping without having to worry finding a bathroom....Don’t have that constant urgency....Great product!!”
“…since I began taking UCP, I no longer get up several times a night to use the restroom!”
Great relief!
“Semaine started working within a day! After the drugstore brand … did nothing for me, I went looking for something better. … I no longer have to worry about leaks or getting up in the middle of the night, which used to happen up to 3 times. …”
Really Works
“This supplement really seems to help. I wake up to pee in the night noticeably less often, which is great.…”
“I think it is helping me right away, I don’t have to get up in the night now”
Seems to help with urgency
“So far, so good. Definitely has helped with my sense of urgency and frequency. I’ve only been taking the uti supplement for about a month. ✅”
In our study of 48 women, 83% reported less bladder irritation by month 2.*
64% of women reported less bladder irritation in month 1. Fewer night trips followed, for more women every month through month 3.*
One capsule a day. That’s the whole routine.
What a customer said
“…I was having to run to the bathroom a lot, plus waking every few hours to go. … With your product, I am back to sleeping 5 hours or more before needing to get up. … after this first bottle, I have purchased 2 more. …”
Women reporting, month 1*Less bladder irritation 64%Fewer night trips 46%
Keep going. Night trips improved for 59% of women in month 2, up from 46%.*
Women reporting, month 2*Less bladder irritation 83%Fewer night trips 59%
Bottle 3: most women in our study reported fewer night trips by month 3.*
Women reporting, month 3*Less bladder irritation 83%
Month 4 and on
Your next delivery keeps you going. By month 4, 81% reported fewer nighttime bathroom trips.*
Three bottles take you to month 3, where the nights turned.
Start tomorrow and you’d reach month 3 around December 22.
*Self-reported, consumer perception study of 48 women aged 45+.
In our study, 64% of women reported less bladder irritation in month 1, and most reported fewer nighttime bathroom trips by month 3.* 1 capsule a day. Free shipping on the 3-month supply. See a difference in 90 days, or your money back.
Recommended: covers you through month 3
3 bottles · 90 days · 1 capsule a day
$69.91 every 3 months
$23.30 a bottle · $0.78 a day · Save $23.06 off $92.97
Save 25%Free shipping
You’d reach month 3 around December 22
Subscription. Renews every 3 months at $69.91. Skip or cancel anytime.
One-time purchase
30 days · 1 capsule a day
$30.99 one time
$1.03 a day
One bottle covers month 1, when 64% of women reported less bladder irritation. Night trips kept improving through month 4.*
Take Urinary Tract Cleanse & Protect every day for up to 90 days. If you don’t see a change, email us and we’ll refund every cent. No fine print.
support@semainehealth.com
Most women in our study reported fewer nighttime bathroom trips by month 3, and 81% by month 4.* Urinary Tract Cleanse & Protect supports a calmer urinary environment, so “full” comes when it should. Fewer 3am signals is the goal. Deeper sleep is what women tell us follows.
64% of women reported less bladder irritation in month 1, and 83% by month 2.* Then the nights catch up: most women reported fewer nighttime bathroom trips by month 3.* Three bottles take you there.
Less water means less volume. It doesn’t move an early signal back. When the bladder’s environment is irritated, a smaller amount can still trigger the same wake-up. Urinary Tract Cleanse & Protect supports the bladder environment behind that signal.
Most standard cranberry extracts absorb poorly, so their working compounds pass through before enough reaches the bladder. Ours is a patented phytosome, Anthocran® by Indena, which wraps those compounds so they absorb about three times better. In a clinical study of our cranberry, biofilm growth in urine was reduced by up to 55% after just 1 week.†
Urinary Tract Cleanse & Protect supports urinary tract health and may help reduce recurrent UTIs. In a 6-month study of our cranberry phytosome in postmenopausal women, there were 83% fewer UTIs than with placebo.‡ If you have signs of an active infection, like fever, back pain or blood in your urine, see a healthcare professional promptly.
One capsule a day, with or without food, at any time of day. There’s nothing to time around bedtime. Each capsule has 120 mg cranberry phytosome (Anthocran® by Indena) and 240 mg hibiscus flower extract (4:1). Other ingredients: vegetable cellulose (capsule), rice flour, calcium palmitate. 30 capsules per bottle.
Check with your healthcare professional before starting. If you take prescription medication, ask your pharmacist too: hibiscus can interact with some drugs at high doses.
Yes. $69.91 every 3 months. Skip or cancel from your account anytime. Prefer not to subscribe? The single bottle and the one-time 3-pack are right above.
Yes, if your bladder changed in your 40s or later. The women in our study were 45 and over, and 83% reported less bladder irritation by month 2.*
Cutting water and sleep aids work around the 3am wake-up. The signal behind it comes from your bladder. Urinary Tract Cleanse & Protect supports your bladder every day: one capsule a day, three bottles to reach month 3, when most women in our study reported fewer nighttime bathroom trips.* See a difference in 90 days, or your money back.
Get 3 Months: $69.91P.S. Every week you wait is another week of lying awake at 3:15 and going to bed thirsty. One capsule tomorrow is the easiest place to start.
*Self-reported results from a five-month consumer perception study of 48 women aged 45+ taking Urinary Tract Cleanse & Protect daily. Open-label, no placebo comparison. “Fewer nighttime bathroom trips” is the study’s nighttime urination item; “less bladder irritation” is its bladder irritation/burning item. Percentages show women reporting improvement, not the size of change. Individual results vary.
†Double-blind, cross-over study of the cranberry phytosome in this formula, in healthy volunteers. Separate from the consumer perception study.
‡Placebo-controlled 6-month study of 120 mg/day cranberry phytosome in postmenopausal women taking SGLT-2 inhibitors. Separate from the consumer perception study.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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