Co-Founder & Chief Science Officer

Matt Crane, PhD
Co-Founder and Chief Science Officer
Bioengineering / quantitative and cellular aging biology
“I've seen how often women's health gets dismissed. My wife, Lauren, needed real answers, and instead, we found gaps and vague guidance. As a partner and researcher, I want to help change that.”
Current affiliation
Semaine Health (Co-Founder, Chief Science Officer)
Education and training
PhD, Bioengineering, Georgia Institute of Technology; postdoctoral research fellow / acting instructor, University of Edinburgh; senior fellow (postdoctoral trainee), Department of Pathology, University of Washington School of Medicine
Selected publications
- Chung K, Crane MM, Lu H. Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans. Nat Methods. 2008;5(7):637-643.
- Crane MM, Stirman JN, Ou CY, Kurshan PT, Rehg JM, Shen K, Lu H. Autonomous screening of C. elegans identifies genes implicated in synaptogenesis. Nat Methods. 2012;9(10):977-980.
- Rempel IL, Crane MM, Thaller DJ, Mishra A, Jansen DPM, Janssens G, et al. Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics. eLife. 2019;8:e48186.
- Crane MM, Russell AE, Schafer BJ, Blue BW, Whalen R, Almazan J, et al. DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during aging. eLife. 2019;8:e50778.