A founder’s perspective on perimenopause
You don’t need hot flashes to be in perimenopause.
Perimenopause can begin in your mid to late 30s with sleeplessness, more anxiety, migraines, or brain fog, years before the symptoms most of us were taught to expect.
Shop Peri/Meno EssentialsPeri/Menopause Essentials · daily multi-system support
*Based on an independent 3-month open-label study of 42 women experiencing 3+ hot flashes a day (NCT05617287).
Reason 1
Sleepless nights, anxiety, brain fog: they start years before hot flashes
Hot flashes and a missing period are not the only signs. Hormones can start shifting in your mid to late 30s, and the first changes may show up in your sleep, mood, head, or focus.
The earlier signs count, even when your cycle still looks familiar.
Reason 2
You could be in perimenopause for over a decade
The average age to start perimenopause is 41. The average age to reach menopause is 50 to 51, which means many women experience hormonal shifts for more than 10 years.
This is a long transition, not a single before-and-after moment.
Reason 3
The earlier you start, the easier this era gets
Supporting these changes early is an investment in the years ahead. As the founder explains, paying attention to earlier symptoms can help you navigate menopause and postmenopause with more fluency.
You do not have to wait for symptoms to become unmistakable before supporting your body.
Reason 4
Not ready for HRT? Red clover can support the same hormones
If HRT feels premature at 38 or 42, a supplement can be one way to support changing estrogen and progesterone. Peri/Menopause Essentials includes red clover, a phytoestrogen, to support the body as hormones shift.
It is an option to discuss alongside the choices you make with your clinician, not a replacement for medical care.
Reason 5
Your hormones don't shift alone — your metabolism and heart do too
Our bodies are holistic systems. Estrogen and progesterone are part of the story, while insulin sensitivity and cardiovascular health change during perimenopause and menopause too.
Peri/Menopause Essentials is built for broader cardiometabolic and hormonal support, not only hot flashes.
Founder perspective, not medical advice
Built by women living this transition, too.
Our founder and her twin sister are both currently going through perimenopause, and they were frustrated by how little women are taught about the changes.
“The more you know, the more empowered you feel and you can make the right choices for yourself.”
Advised by a dedicated Medical Advisory Board
We partner with respected experts in gynecology, urology, and beyond who help shape our commitment to rigorous science and accessible, evidence-based education for women.
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Dr. Michael LewisOBGYN
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Dr. Barbara ChubakUrologist
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Dr. Jackie CrowellPT, DPT
Support your changing hormones from within.








Peri/Meno Essentials
Daily support for the hormonal and cardiometabolic changes of perimenopause and menopause, with red clover, bergamot, and olive fruit.
Try it for 90 days, risk-free.
Give your body a full season of consistent support. If you do not love how you feel within 90 days, reach out and we will refund every cent.
Frequently asked questions
Can I start this in my late 30s?
Perimenopause symptoms can begin in the mid to late 30s, even if you still have a regular period and no hot flashes. If you are noticing changes in sleep, anxiety, migraines, or brain fog, bring them to your clinician and ask whether Peri/Menopause Essentials fits your routine.
What about HRT?
It’s a complement to whatever you’re doing with your doctor, not a replacement. Many women take Peri/Meno Essentials alongside HRT. Always loop in your clinician about what’s right for you.
How do I take Peri/Menopause Essentials?
Take 1 capsule daily, with food.
When will I feel a difference?
Most customers notice a difference within the first month of taking Peri/Menopause Essentials. Some of the first changes are better sleep and fewer hot flashes. Month after month, improvements in mood, brain fog, and thicker hair increase. Consistency is key to seeing and feeling results in 3–6 months.
Can I take this with other Semaine supplements?
We designed all our supplements to work effectively together. We are complex humans, so we need different supplements at different stages of life. However, it’s always a good idea to check with your doctor if you are starting any new supplement and taking one or more medications. We have a white paper that you can share with your doctor that explains the formulation, dosage, and clinical trial results: White Papers.